The boundary between Guyana and Suriname follows a series of rivers through remote and sparsely populated rainforests in South America. An operative boundary, approximately 910 kilometers (565 miles) in length, was established by British and Dutch colonial powers, but a number of disputes arose during the colonial period and continue to persist today.

The northern section of the boundary was first established during the late 18th century and was said to follow the western (Guyanese) bank of the Courantyne River. However, Great Britain, and later independent Guyana, intermittently claimed the thalweg of the river as the boundary. This portion does not currently seem to be in dispute, and a 2007 maritime boundary arbitration established the boundary at sea beginning off the western coast of the Courantyne River mouth in the Atlantic Ocean.

Competing claims to sovereignty over an area known as the New River Triangle (Guyana) or the Tigri Area (Suriname) stem from the question over which tributary is the source of the Courantyne River. The British claimed the boundary followed the Kutari River to the east, while the Dutch claimed the New River to the west. The disputed territory is controlled by Guyana, but Suriname continues to claim sovereignty up to the New River.

Guyana and Suriname also have an established maritime boundary.