The majority of the 860 km Mozambique – Tanzania land boundary follows the Rovuma River and has not been demarcated. The 59 km section west of the Rovuma River was demarcated by a German–Portuguese boundary commission in 1907, confirmed in 1909, and follows the Messinge (Msinje) and Shipingue Rivers, a more or less straight overland section, and the Txuinde River to the shore of Lake Malawi. The location of the tripoint with Malawi is disputed.

Mozambique and Tanzania also have an established maritime boundary.